Ok i'll bite:
My instrument cables are all AVID Digidesign Digisnakes, they are pretty much best price performance in db25 multicore cabling, not the best, but no HOSA either.
I can hear the difference between those and my Vandammes, which I use on my mastering chain, my summing signal path and my patchpanel (setting up tne chain)
IMHO, choosing instruments, or choosing sound transport are 2 different discussion. One is around sound design, the other is about accuracy. I hope you understand the difference?
Now, if you do, you can then argue if one is better of with investing more in signal path, or more sources? I cannot answer that question for you, but for me it was signal path in this stage. I don't really need more sources.
Then there is yet another dimension, which is funds and how much you want to spend on a studio. For my purpose I know have a very versatile and balanced setup. I can work both ITB or OTB or hybrid. a pristine signal path is crucial for my setup.
anyway, i have a bunch of redundant hosa, digisnakes and planet waves now on sale. If I would not be hearing a difference, I would not have replaced those.
Esoteric sound for the discerning ear