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-- Chewing E's
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Posted by Transattic on Nov-25-2003 03:55:

quote:
Originally posted by DJ-Fuq
Its a bit more complicated than that.
MDMA binds at the serotonin, norepinephrine (noradrenaline), dopamine, and acetylcholine receptors, and at the serotonin and dopamine transporters (Rivas-Vazquez, Delgado, 2002). It moves through the serotonin pathway, to the cell bodies in the Raphe nucleus and sends long axons to the neocortex, and the limbic system, and also descends the spinal cord to affect the motor neurons (NIDA, 2003).
MDMA's primary mechanism of action is by releasing 5-HT (serotonin)and blocking its reuptake (Palfai, Jankiewicz, 2001). It also increases the net release of norepinephrine, and dopamine, and blocks the reuptake of dopamine (Rivas-Vazquez, Delgado, 2002). MDMA stimulates serotonin efflux from plasma membrane vesicles and secretory vesicles (Rudnick, Wall, 1992). In the plasma membrane vesicles, MDMA inhibits serotonin transport by direct interaction with the sodium dependent transporter. MDMA inhibits ATP-dependent serotonin accumulation and stimulates efflux of previously accumulated serotonin (Rudnick, Wall, 1992). Usually after serotonin is released into the synaptic gap and is used, serotonin transporters move serotonin back into the presynaptic neuron to be metabolized. MDMA prevents the transporters from taking serotonin back into the presynaptic neuron. It can also cause the transporters to work in reverse bringing serotonin into the synaptic gap (NIDA, 2003).
http://www.humboldt.edu/~morgan/mdma_s03.htm


Busting out the Biology and Chemistry!!!
Looks like someone did their research, if not already a scientist.


Posted by jdjd on Nov-25-2003 03:57:

cut and paste


Posted by DJ-Fuq on Nov-25-2003 04:02:

quote:
Originally posted by jdjd
cut and paste


Yeah i only added a couple of things in brackets for clarity


Posted by Transattic on Nov-25-2003 04:03:

what do u mean, bud?


Posted by moncster on Nov-25-2003 04:27:

quote:
Originally posted by jdjd
cut and paste


http://www.humboldt.edu/~morgan/mdma_s03.htm

y halo thar!


Posted by neoh on Nov-25-2003 05:32:

quote:
Originally posted by jdjd
just take g and you dont have to worry about all that
how long does it take for e to 'go bad'!?


E will last forevor, even in warm climates.

- neoh


Posted by A.J. on Nov-25-2003 09:13:

quote:
Originally posted by KilldaDJ
'course i been taking the pills, what do u think ive been doing with them? sticking them up my arse?' ROFL



Have you heard of shelving??? (as in sticking drugs up your ass)


Posted by UglyDave on Nov-25-2003 09:52:

quote:
Originally posted by DJ-Fuq
Its a bit more complicated than that.
MDMA binds at the serotonin, norepinephrine (noradrenaline), dopamine, and acetylcholine receptors, and at the serotonin and dopamine transporters (Rivas-Vazquez, Delgado, 2002). It moves through the serotonin pathway, to the cell bodies in the Raphe nucleus and sends long axons to the neocortex, and the limbic system, and also descends the spinal cord to affect the motor neurons (NIDA, 2003).
MDMA's primary mechanism of action is by releasing 5-HT (serotonin)and blocking its reuptake (Palfai, Jankiewicz, 2001). It also
...
...
...


respect to this guy! he knows everything!!


Posted by PSi on Nov-25-2003 11:36:

quote:
Originally posted by UglyDave
i've heard.. although i'm not sure about how true it is, but.. aparrently, if u stick a pill up ur ass it supposedly gives u a great buzz.

althoigh i'd seriously doubt this, and the actual stuff will have no effect on the part of the body it comes in contact with.. the pills will only affect u when the mdma gets into ur brain and pops all those little cells which hold ur seratonin and and awahey u go!!

UglyDave


yeah when you take a pill up your bum (for the record i havent tried this) it works just as well as say snorting it. The chemicals are easily absorbed by the large amount of blood running around your anal Spongebob.

Note of advice: dont chew pills, let your ass do the chewing for you.

later,
PSi


Posted by wick on Nov-25-2003 12:40:

most of you guys are bloody idiots.
THERE IS NO COKE IN PILLS. THE FUCKING END!

there is no point. the ammount of coke you need to feel anything from when you orally administer a pill is a lot more than a pill size could hold! you would need a GIANT pill to feel the coke.
plus why the fuck would the cook of the pill put coke in there then sell the pill for the same price? when he could sell the coke alone for FAR more than a pill.
geezus people, get ur facts straight!!

Pettiscool - i dont know the answer to ur question, but visit www.bluelight.nu . youll definetly get an answer there.


Posted by Roddy on Nov-25-2003 15:54:

quote:
Originally posted by UglyDave
might make u come up a bit quicker, but it shouldn't affect the way ur ass feels..

my mum stuck a thermometer up my ass once to take my temperature
..i was about 3 at the time.. think i bit the last one so she wasn't takin the chance with this one!!

..hope nobody stuck it under their tongue after i used it


I stuck my dick up ur Mas Ass once, it was for pleasure Only Jokin Dave back to the topic of Chewing wingers, why would u wanna do it, it is one of the worst tastes in the world,if not the worst, dunno why ur mouth went numb for maybe because the taste is so bitter??


Posted by drizzt81 on Nov-25-2003 16:16:

quote:
Originally posted by UWM
Yeah and some of the other ones that are 4 parts caffeine to one part speed ... how wonderful
neato.. now they one need to reverse the ratio and it'd be a fun pill.


Posted by drizzt81 on Nov-25-2003 16:22:

quote:
Originally posted by neoh
E will last forevor, even in warm climates.

- neoh
is E hygroscopic? should it be kept dry?


Posted by Mike_B on Nov-25-2003 21:44:

quote:
Originally posted by wick
most of you guys are bloody idiots.
THERE IS NO COKE IN PILLS. THE FUCKING END!

there is no point. the ammount of coke you need to feel anything from when you orally administer a pill is a lot more than a pill size could hold! you would need a GIANT pill to feel the coke.
plus why the fuck would the cook of the pill put coke in there then sell the pill for the same price? when he could sell the coke alone for FAR more than a pill.
geezus people, get ur facts straight!!

Pettiscool - i dont know the answer to ur question, but visit www.bluelight.nu . youll definetly get an answer there.


your about 3 pages too late lol


Posted by neoh on Nov-25-2003 22:09:

quote:
Originally posted by drizzt81
is E hygroscopic? should it be kept dry?


pretty much anything is, especially pills. Would you eat a pill that's been sitting on your shelf for a year? Doesen't matter what it is.. always keep it stored in a good place, that's just common sense.


Posted by kr00t0n on Nov-25-2003 22:18:

PIlls up arse = Longer come up, general more fuckedness and it lasts longer.

Only dis comfort is getting the little bugger up there, but its fine after 2 or so minutes, as they are pretty small.

As for the chewing as to come up quicker, why not just crush the bastid, and put him in an empty capsule. That way, no shitty taste, and as soon as you dissolve through the cap, the powder gets absorbed super quick like, as apposed to digesting the pill

Or parachute if you canna find/afford caps, little bit o toilet paper/rizla and down with water.


Posted by Transattic on Nov-26-2003 00:31:

to solve that problem the manufacturers could make it candie flavored on the outside!!! It makes you want to eat more!


Posted by UWM on Nov-26-2003 00:35:

quote:
Originally posted by kr00t0n
PIlls up arse = Longer come up, general more fuckedness and it lasts longer.

Only dis comfort is getting the little bugger up there, but its fine after 2 or so minutes, as they are pretty small.


Something tells me someone has experience in the matter.

We have a weiner ... er ... winner!


Posted by neoh on Nov-26-2003 01:12:

quote:
Originally posted by Transattic
to solve that problem the manufacturers could make it candie flavored on the outside!!! It makes you want to eat more!


dip em in chocolate.

seems as thou kr00t0n did it.


Posted by Orbax on Nov-26-2003 03:17:

what if you put them in your urethra?


Posted by kr00t0n on Nov-26-2003 20:15:

quote:
Originally posted by Orbax
what if you put them in your urethra?


Sounds like it could be rather painful, and prolly not work.

And yes I have tried shoving, I feel better making opinions based on my experiences, and can thereby answer ppls questions better


Posted by Transattic on Nov-27-2003 00:05:

now if you were a chick that would make it sexy!


Posted by digitalbreach on Nov-27-2003 07:04:

quote:
Originally posted by neoh
chewing E makes you high much quicker, this way the pill doesent desolve in your stomach.



goota agree with you. chewing them does make your high come quicker.
From the many times that I chewed them don't remember my mouth being numb. only a nasty taste that I usually washed down with good ol' Orange juice. from what I remember the nastier (sour taste) the pill tasted the better the roll. only time my mouth felt numb was the next day from chewing on candy/gum and mouth clenching. maybe thats it.

It's been a while though. (gotta stop urges)


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