TranceAddict Forums (www.tranceaddict.com/forums)
- Canada - Toronto & Southern Ont.
-- Sad story
Pages (4): « 1 2 3 [4]

source

The psychological and physiological effects of MDMA on normal volunteers.

Downing J.

The experimental subjects were older than the average general population, more educated and considerably experienced in drug use. They considered themselves to have benefited by their MDMA experience, with no evidence of harm. There were moderate, consistent biochemical, cardiovascular and neurobehavioral changes within normal limits that peaked between one and two hours following ingestion, returning to predrug levels within 24 hours. This experimental situation produced no observed or reported psychological or physiological damage, either during the 24-hour study period or during the three-month follow-up period. While the subjects are not typical of the general population, the findings support the general impression among knowledgeable professionals that MDMA is reasonably safe, produces positive mood changes in users, does not cause negative problems (if used sparingly and episodically) and is without evidence of abuse. Certainly, any drug that causes ataxia, elevates blood pressure and pulse is potentially unsafe. One can say little about safety when effects and side effects are studied for only 24 hours and then a blood cytology is obtained after three months. In this study, safety must exclude long-term toxicity. Not enough is known about MDMA's long-range effects other than information from random anecdotal evidence supplied by a few clinicians plus self-reports by unselected and unsupervised users. From the information presented here, one can only say that MDMA, at the doses tested, has remarkably consistent and predictable psychological effects that are transient and free of clinically apparent major toxicity. The experimental subjects believed that MDMA is both safe and beneficial, but there is insufficient evidence to accurately judge either the drug's potential harm or benefit.

These are the side effects for the other drugs:



Illicit Drugs



Overview of Criminal Activity

Methamphetamine

Methamphetamine use is on the increase in many parts of the country, but primarily in Western Canada.The bulk of this methamphetamine is manufactured domestically in Canada in small clandestine laboratories, though larger operations capable of producing 4.54 kg or more in one production cycle have been encountered occasionally. Given that pseudoephedrine (PSE), an essential ingredient in the manufacture of methamphetamine, is available in over the counter medications (in pharmacies and over the Internet) several provincial governments have taken steps to limit their availability. Organized crime groups involved in the illicit methamphetamine industry include outlaw motorcycle gangs, specific Asian crime groups, and independent organized crime groups.

Negative Socio-economic Effects

The overall impacts of the illicit drug trade are varied and substantive affecting individuals and their communities.While many of these negative effects may be difficult to quantify, their harm is real and substantive. In general terms, the illicit drug trade has impacts on a user�s health; brings about additional medical costs; demands greater law enforcement resources; and may incite conflict and violence between users and organized crime groups; in addition to negatively affecting family and friends. Moreover, in order to feed their habits, addicts can commit a number of petty and serious crimes such as robbery and assault, break-and-enters, the sale of stolen property and prostitution.

Each illicit drug has a combination of side effects that bring about both a physical and psychological dependence.A tolerance can be developed from addictive drugs, such as methamphetamine, that may force the user to acquire larger doses and/or use with greater frequency in attempts to experience what they believed were the positive effects of the drug. Injected drugs, such as cocaine and heroin, may enhance the risk of various blood-borne infections (eg. HIV/AIDS; hepatitis B and C), scarred or collapsed veins, infection of the heart lining and valves, abscesses, pneumonia, tuberculosis, and liver and kidney disease.Although ecstasy is not known to create physical dependency, health-related side effects including dehydration or hyperthermia have occurred while using the drug at raves and dances, leading to death due to kidney failure and heart attack.

Health risks are heightened due to the unpredictability of ingredients within illicit drugs. As a result, consumers do not always know the actual contents of the illicit drug they have purchased nor the purity level of the drug.Their intended drug purchase could be laced with other illicit drugs and/or chemicals or contaminated by fungi or moulds.An unknown drug combination can cause serious adverse affects, including death.Aside from these medical problems, illicit drug users can also encounter serious legal problems, such as a criminal sentence and subsequent record, which could affect their future employment and travel opportunities.

The manufacturing of illicit drugs, specifically synthetic drugs and marihuana, pose threats to public safety and to law enforcement and the health services sector, as well as certain environmental risks. For instance, the chemicals used in the manufacture of methamphetamine are hazardous with some being highly volatile and at risk to ignite or explode if mixed or stored improperly.Any resultant fire or explosion not only harms the individuals involved with at the laboratory but also the neighbouring area, its inhabitants and visitors.

Exposure to the toxic chemicals used in the manufacture of methamphetamine could cause intoxication, dizziness, nausea, disorientation, lack of coordination, pulmonary edema, serious respiratory problems, severe chemical burns, and damage to internal organs. Methamphetamine production also threatens the environment as a typical laboratory may produce 2.3 kg to 3.2 kg of toxic waste for every one pound of methamphetamine produced.The improper disposal of this toxic waste could cause contamination of the soil and any nearby water supplies.

Marihuana grow operations pose a number of health and safety risks to the occupants of the residences in which cultivation occurs, to their neighbours and surrounding community.The health risks are linked to the increased fire hazard these grow houses represent to themselves and their neighbours.A recent study of grow operations in B.C. concluded that a fire was 24 times more likely to occur in a grow house than in an ordinary dwelling largely because of the unsafe electrical diversions or bypasses many grow operators use to circumvent utility meters in order to steal electricity.They are also linked to the moulds which result from the intense humidity and chemicals used in indoor marihuana grow operations. Homes that have housed grow operations often require great effort and expense to rid them of the moulds and other residues which would otherwise make them unsafe to live in.

In terms of safety risks, neighbours and grow house operators run the risk of being victimized in a �grow rip�, which occur when a rival group or individuals violently steal a mature crop. Grow rips can entail assaults, kidnappings and the use of weapons including firearms. Safety issues are also linked to the occasional use of booby traps by grow house operators seeking to protect themselves from potential thieves.



source: ACIS - A division of the RCMP

drugs are bad - end of story.

quote:

Originally posted by AC-Milan It is clear here that you were justifying the use of MDMA. Now, my question is: What makes someone who is dropping E better than someone who is doing G once in a great while?

Because G is MUCH riskier, and has a much higher occurance of scary side effects. A good percentage of G users have woken up in the hospital. Can't say the same about other things, can you? When do u see people going into an "E hole" or "E'ing out" into unconciousness??

G is frightening shit, and shouldn't be messed with. The slightest miscalculation of dosage and you're facked.

G= garbage.

quote:

Originally posted by tatgirl Because G is MUCH riskier, and has a much higher occurance of scary side effects. A good percentage of G users have woken up in the hospital. Can't say the same about other things, can you? When do u see people going into an "E hole" or "E'ing out" into unconciousness?? G is frightening shit, and shouldn't be messed with. The slightest miscalculation of dosage and you're facked. G= garbage.

+1

It's messing with your GABA receptors in your brain, hmmm not a good thing.

quote:

Originally posted by Mako +1 It's messing with your GABA receptors in your brain, hmmm not a good thing.

make it +2.

and since quality can change from batch to batch it makes it even riskier to calculate the proper doses. I've had to baby sit for people G'd out way too many times.
One night in montreal there was a couple out of thier tree at the club sitting on the side. They couldn't even speak to me or keep thier eyes open for more than a second, so I just sat with them to keep an eye out for them to make sure things didn't get worse and risk an OD (they were looking pretty close to it at this point so I had to keep checking for breathing). A little later on the guy starts slowly coming around and begins saying how messed up he is. Apparently the girl is his girlfriend. He finally gets up to leave saying that just tell her to meet me at home and walks out. A bit later the girl comes around. She had NEVER been to montreal before and had no idea how to find her way back to his house and couldn't remember his phone number since he had just moved there and she didn't think she would need it since they were going out together that night. Needless to say I got to bed at around 1pm that next afternoon after taking this poor girl with no money out for breakfast to try and calm her down a bit.
I've had similar experiences in NYC, Toronto and a few other cities. Yes there are some people who seem to be ok on it in SMALL doses but in general all signs point to a bad night, full of risks, and making the greatest impressions on others when you get like that.
Please think it through and be carefull.

My first time seeing someone G out...

I actually saw 4 people G out at one afterparty...

it was scary and fucked up.

quote:

Originally posted by Mako +1 It's messing with your GABA receptors in your brain, hmmm not a good thing.

It's not really because it's messing with GABA... Alcohol messes with the GABA system too and my benzo pills (ativan) target GABA as well, and that's their intended function.

quote:

Originally posted by daves It's not really because it's messing with GABA... Alcohol messes with the GABA system too and my benzo pills (ativan) target GABA as well, and that's their intended function.

Yes but in a different ways than the benzo pills and alcohol, I think you took it the wrong way, i'm not saying messing with GABA receptors in general will fuck someone over, just the way GHB does it. And its relationship with the GABA neurotransmitter itself (i.e. being the precursor to it) that makes is messed up.

Btw are those benzo pills similar to Valium?

yeah ativan is lorazepam, very similar to diazepam (valium) - i just have the remaining pills left from last prescrip - but dont actually need them anymore. short-term relief of the more extreme panic attack symptoms.

Powered by: vBulletin
Copyright © 2000-2021, Jelsoft Enterprises Ltd.