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-- VICE Special Report: Killing Cancer
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You're right, but I think the approach of using differently engineered viruses for different cancers that manifest and replicate in differnt ways is going to be the key.

In the vid, one of the methods is to use the virus to make radioactive iodine bind to the cancer cells, thus killing them but not the surrounding or alternative tissues. Another was harnessing the virus to make the body itself (via white blood cells) attack the tumorous growths.

It's not about one vaccine to fir them all, but more about an approach of harnessing something that would normally infect us, infect a specific type of cell, in this cancer.

The FDA will actually allow fast tracking via their FTD program but the problem is it that it requires far more bureaucracy - you have to meet far more frequently and many more times with FDA officials, the burden of paperwork increases 5 fold and the dumb thing is, all these are costs to the developer.

You'd think that if you come up with something that meets the FTD criteria (it's for a serious and life-threatening condition, the initial trials have shown measurable promise, decreasing a clinically significant toxicity of an available treatment etc), the FDA would themselves put more effort in to take the burden off the developer but sadly it's not the case. Some smaller biotech firms simply don't have the resources to get through the FTD program.

Apparently last year there were less than 100 applications

quote:

Originally posted by DJ RANN I think the approach of using differently engineered viruses for different cancers that manifest and replicate in differnt ways is going to be the key.[quote] I believe that eventually it will come down to cheap and fast methods of prophylaxis. The miracle cure for cancer...seems a bit too unrealistic. [quote]In the vid, one of the methods is to use the virus to make radioactive iodine bind to the cancer cells, thus killing them but not the surrounding or alternative tissues. Another was harnessing the virus to make the body itself (via white blood cells) attack the tumorous growths... infect a specific type of cell, in this cancer.

That's the problem, cancer-cells although being mutated are still viewed as 'self'. To engineer such a virus would be a next to impossible task - yet I digress, the experts know better than me it will be interesting to see how it progresses.

quote:

The FDA will actually allow fast tracking via their FTD program but the problem is it that it requires far more bureaucracy - you have to meet far more frequently and many more times with FDA officials, the burden of paperwork increases 5 fold and the dumb thing is, all these are costs to the developer. You'd think that if you come up with something that meets the FTD criteria (it's for a serious and life-threatening condition, the initial trials have shown measurable promise, decreasing a clinically significant toxicity of an available treatment etc), the FDA would themselves put more effort in to take the burden off the developer but sadly it's not the case. Some smaller biotech firms simply don't have the resources to get through the FTD program. Apparently last year there were less than 100 applications

From what I've read, most of these small-time labs wielding a profitable result end up being incorporated into the bigger firms. Buy-overs.

Speaking of pharmaceuticals, what the fuck happened to Fledz??

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