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-- Pot may indeed lead to heroin use, rat study shows
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Posted by starsearcher on Jul-13-2006 14:24:

Read This! Pot may indeed lead to heroin use, rat study shows

quote:

Pot may indeed lead to heroin use, rat study shows

By Anne Harding Wed Jul 12, 1:43 PM ET

NEW YORK (Reuters Health) - Teens who experiment with marijuana may be making themselves more vulnerable to heroin addiction later in life, if the findings from experiments with rats are any indication.

"Cannabis has very long-term, enduring effects on the brain," Dr. Yasmin Hurd of the Mount Sinai School of Medicine in New York, the study's lead author, told Reuters Health in an interview.

Whether or not trying marijuana is a 'gateway' to use of so-called harder drugs like heroin and cocaine has been hotly debated, she and her colleagues note in the journal Neuropsychopharmacology.

To investigate whether pot smoking could cause brain changes that might predispose an individual to later drug use, Hurd and her team looked at rats exposed to the active ingredient in marijuana, THC, during a developmental period similar to human adolescence. To mimic the relatively small amount used by most teens experimenting with pot, the rodents received periodic, small doses of THC.

As young adults, the animals were fitted with catheters that allowed them to self-administer heroin. The researchers compared the amount and frequency of their drug use with that of rats that had not been given THC previously.

The THC-exposed rats were more sensitive to the effects of heroin, the researchers found, and also consistently used larger amounts of the drug.

The researchers also found that the THC-exposed rats showed disturbances in the brain's endogenous opioid system, which is often popularly referred to as the "reward system" of the brain and, in humans, is involved in experiencing pleasure.

"I was really surprised at how specific and enduring the effects of cannabis were," Hurd said.

She and her colleagues conclude: "The current findings provide direct evidence in support of the gateway hypothesis that adolescent cannabis exposure contributes to greater heroin intake in adulthood."

SOURCE: Neuropsychopharmacology


Posted by jon jon on Jul-13-2006 14:50:

omg please LOL this is so past retarded I don't even know where to start...


Posted by Cosmic Fur on Jul-13-2006 14:50:

Bullshit. The difference betwween us and the rats is that we don't have self-administering doses of heroin attached to us. I think the decision to try heroin in humans is independent of the decision to try pot.


Posted by MKpacha on Jul-13-2006 14:51:

Re: Pot may indeed lead to heroin use, rat study shows

quote:
Originally posted by starsearcher




seriously... dont make yourself sound more stupid by posting shit like this.

this is so far fetched.


Posted by starsearcher on Jul-13-2006 14:58:

Re: Re: Pot may indeed lead to heroin use, rat study shows

quote:
Originally posted by MKpacha
seriously... dont make yourself sound more stupid by posting shit like this.

this is so far fetched.




http://news.yahoo.com/s/nm/20060712...HNlYwNtZW5ld3M-

Seriously...myob


Posted by preppie chick on Jul-13-2006 15:02:


Posted by MKpacha on Jul-13-2006 15:03:

Re: Re: Re: Pot may indeed lead to heroin use, rat study shows

quote:
Originally posted by starsearcher


http://news.yahoo.com/s/nm/20060712...HNlYwNtZW5ld3M-

Seriously...myob



if you wana make heroin your business dude, so be it.

or trance


Posted by DigDeep on Jul-13-2006 15:03:

Re: Re: Pot may indeed lead to heroin use, rat study shows

quote:
Originally posted by MKpacha
seriously... dont make yourself sound more stupid by posting shit like this.



seems a little harsh? lol

he's posting an article, fuck.


Posted by *~LiSa-LoO~* on Jul-13-2006 15:04:

I think the key words in this study are: RAT study

I am not a rat. I may smoke pot but I do NOT want to try heroin.


Posted by Cosmic Fur on Jul-13-2006 15:05:

That time of the month, MKPacha?


Posted by MKpacha on Jul-13-2006 15:05:

Re: Re: Re: Pot may indeed lead to heroin use, rat study shows

quote:
Originally posted by Floorwhore
seems a little harsh? lol

he's posting an article, fuck.



not meant to be harsh at all, sorry. I just saw him to be more intellegent... this article is just plain dumb.


Posted by Time2Burn on Jul-13-2006 15:05:

Holy Crap!

I

NEED

SMACK!

NOW!!!!!!!!


Posted by MKpacha on Jul-13-2006 15:06:

quote:
Originally posted by Cosmic Fur
That time of the month, MKPacha?



lol Dima, im actually starting to like u


Posted by Elendil on Jul-13-2006 15:07:

I certainly agree that a tendancy towards common marijuana usage would definitely correlate to an increase in the experimentation with other substances; however, I don't think the line is drawn always towards the vile and dangerous substances - hell, Marijuana usage also leads people to incredibly beneficial and powerful substances like Mushrooms, Peyote, LSD, DMT, Ayuhuasca, Salvia, etc... I can't disagree with the gateway theory, but it's not always a gateway to "puuuuuure eeeeeeeeevil!", it's simply a doorway to realms. However, if cannibis does indeed impact the brains ability to reach reward states, or happiness, then there is no doubt that the easiest of the pleasure-inducers, Heroin and Cocaine being the mainstays, will be the path most walked. Mushrooms and the like, though they lead to more enduring, more inspiring and full-bodied happiness, are much more difficult to manage. This is a society of "path of least resistance" after all.


Posted by Cosmic Fur on Jul-13-2006 15:10:

quote:
Originally posted by MKpacha
lol Dima, im actually starting to like u


Damn.


Posted by weema on Jul-13-2006 15:16:

Re: Re: Re: Re: Pot may indeed lead to heroin use, rat study shows

quote:
Originally posted by MKpacha
not meant to be harsh at all, sorry. I just saw him to be more intellegent... this article is just plain dumb.


If you "saw him to be more intellegent" then why did you say "dont make yourself sound more stupid"

lol, in any case, relax, it's just an article. He never said he agreed with it, he was just sharing a piece of text he found interesting, it's a neutral action.

I personally find it to be rubbish.


Posted by DigDeep on Jul-13-2006 15:21:

Re: Re: Re: Re: Re: Pot may indeed lead to heroin use, rat study shows

quote:
Originally posted by weema
If you "saw him to be more intellegent" then why did you say "dont make yourself sound more stupid"

lol, in any case, relax, it's just an article. He never said he agreed with it, he was just sharing a piece of text he found interesting, it's a neutral action.

I personally find it to be rubbish.



pwned.

its not like he said her mother was dirty and gave him stinkdink!?

apparently, that one flew under the radar - lmao


Posted by MKpacha on Jul-13-2006 15:22:

Re: Re: Re: Re: Re: Re: Pot may indeed lead to heroin use, rat study shows

quote:
Originally posted by Floorwhore
pwned.

its not like he said her mother was dirty and gave him stinkdink!?

apparently, that one flew under the radar - lmao




da dip.




hey jon, sorry dude.


Posted by DigDeep on Jul-13-2006 15:24:

Re: Re: Re: Re: Re: Re: Re: Pot may indeed lead to heroin use, rat study shows

quote:
Originally posted by MKpacha
da stink dip.


Posted by Moral Hazard on Jul-13-2006 15:29:

When I read the title I got this great little image of a rat sitting in a low rent appartment with no furniture other then a urine stained mattress cooking up over a candle. I'll be laughing at that all day.


Posted by MarkT on Jul-13-2006 16:05:

quote:
Originally posted by jon jon
omg please LOL this is so past retarded I don't even know where to start...


+ 1

the study itself is fine, IMHO, but the application to humans is absurd.

1. You can extrapoloate PHYSIOLOGICAL comparisons with rats...but human beings can REASON to a far greater depth. i.e. a teen or adult can more readily differentiate between the dangers of heroin use over pot...the social stigma...cost...etc.

2. Availability. Heroin isn't *nearly* as readily available as pot. So, unless we afix a catheter of heroin to people, or otherwise make it as readily available as pot (actually, moreso in this study since the rats were periodically given pot, while they could self-administer heroin WHENEVER THEY WANTED), and reduce stocial stigma, etc. etc. then the application of the results is seriously flawed.

Both of those points don't invalidate the study's results themselves...just the absurd application re: the "gateway drug" label put on pot.

All this shows is that from pot use, you MAY respond more positively IF you then use heroin. It demonstrates NOTHING with regard to pot being a "gateway drug" in the sense that opponents of pot claim that people will then move on to other drugs once they've tried pot.

I smoke pot. You don't. IF we both try heroin, I'll probably like and use it more.

so what? it does NOT follow that because I smoke pot, that I am more likely to use heroin than someone who doesn't smoke pot.


Posted by StereoPrincess on Jul-13-2006 21:08:

i hate when reputable journals fall to the pressures of conservative society and publish shit like this.


Posted by slingshot on Jul-13-2006 21:15:

does anybody know where i can find some methadone?


Posted by neuromancer on Jul-13-2006 21:25:

talking about rats there is this little experiment that i like to remind to my druggie friends .

- basically they hook an electrode to a pleasure center in the rat's brain and everytime the rats push a button a device sends an stimulus to the pleasure center. you know what happens ehh .. the rat dies pushing the button, nothing else is important anymore..

here is a link to a couple of videos of rat experiments:

The Electrical Stimulation of Brain Pleasure Centers (videoclips of Experiments )


Posted by dallastar on Jul-13-2006 21:31:

quote:
Originally posted by slingshot
does anybody know where i can find some methadone?


umm, college and spadina maybe? hee hee


I love to smoke WEEEEEEED, but I would NEver, ever, ever EVER do HERoin or Meth, or crystal . . .. yadda yadda yadda!


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