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Ecstasy in moderation alleviates depression?

2 years old, but a cool find nevertheless. According to the study (link below), a low dose of e (approx 1.5 tabs) taken at time intervals of > 2 weeks may help improve depression symptoms by as much as 28%. Does anyone know anything else about this? (personal experiences are welcome)


Study link: http://thedea.org/docs/2006_de_Win22871_1.pdf

quote:

The preliminary results from an ongoing Dutch study also indicate that the very moderate use of Ecstasy alleviates symptoms of depression by 28% and improved users' overall mental state. These users also appear to be free of neurological injury of any kind.

(src: wiki mdma page).

I'd argue that ecstasy in large doses also alleviates depression.

wtf ? how does removing serotonin from your brain alleviate depression? I think this is bs.

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Originally posted by Dj Nacht wtf ? how does removing serotonin from your brain alleviate depression? I think this is bs.

^Yeah, you would think it would do just the opposite, from a psysiological side...

Always makes me happy.

I mean, my friend always says it makes him happy.

quote:

Originally posted by Dj Nacht wtf ? how does removing serotonin from your brain alleviate depression? I think this is bs.

Perhaps (I don't know for sure I'm not a Psychiatrist) due to the mind not releasing any or very low amounts of Serotonin when in a depressed state. I'm pretty sure the Serotonin needs to be released for the brain to actually use it (talkin' outta my ass right now, anyone know if I'm right on this or not?).

Since Ectasy releases Serotonin at a higher-than-normal rate, I could see it helping people overcome depression symptoms when on it. And may also help the brain into releasing normal levels of Serotonin afterwards?

It's a load of shit.

Short term (i.e today only); yes, ecstasy can make you "happy".

Long term, ecstasy is a major contributor to depression.

quote:

Originally posted by Beat Blog It's a load of shit. Short term (i.e today only); yes, ecstasy can make you "happy". Long term, ecstasy is a major contributor to depression.

Only someone depressed from taking too much ecstasy would have such a depressing outlook on taking ecstasy.

quote:

Originally posted by Beat Blog It's a load of shit. Short term (i.e today only); yes, ecstasy can make you "happy". Long term, ecstasy is a major contributor to depression.

dingg
its not like you have an unlimited supply of ecstacy. yes, ecstacy helps release seratonin and yes, depression can be caused by not having enough seratonin released. however, ecstacy will most like release too much, leaving you even worse off after the comedown. from everything that i know of it, taking ecstacy is an absolutely terrible idea if you already have a seratonin inbalance, it'll only serve to fuck it up further

quote:

Originally posted by Beat Blog It's a load of shit. Short term (i.e today only); yes, ecstasy can make you "happy". Long term, ecstasy is a major contributor to depression.

I don't know if I can completely agree with you on that. Although studies tend to agree with your point of view in this debate. They have later been found to be quite biassed.

I do agree that if you become dependant on any form of substance it can change your overall mental state. I would also argue though, that depression may have led said user to use Ecstasy without moderation in the first place.

So, i just finished skimming the study, and it turns out that the decreased levels of depression was determined solely from self-administered questionnaires give to the test subjects; not very reliable.

quote:

Originally posted by silene So, i just finished skimming the study, and it turns out that the decreased levels of depression was determined solely from self-administered questionnaires give to the test subjects; not very reliable.

hahaha seriously?
wonder if they gave them the questionnaire before they came down

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Originally posted by mezzir hahaha seriously? wonder if they gave them the questionnaire before they came down

that'd be great.

The abstract says that the overall trial period was 8.1 +/- 6.5 months and the followup after the last e use was 7.7 +/- 4.4 weeks. Still, there were no tests done on hormone levels and other shit that might somehow accurately determine the subject's level of depression.

Fuck...

quote:

Originally posted by silene that'd be great. The abstract says that the overall trial period was 8.1 +/- 6.5 months and the followup after the last e use was 7.7 +/- 4.4 weeks. Still, there were no tests done on hormone levels and other shit that might somehow accurately determine the subject's level of depression. Fuck...

I dunno, if a person doesn't feel sad anymore, wouldn't you say they are no longer depressed? Depression is really subjective. You can't judge it based purely on hormone levels.

I could easily see good experiences on E helping people get perspective on issues which may be causing their depression, which could help them become un-depressed in the future.

bollocks.

If you by extacy mean the tablets of unknown origin floating around parties at a tenner a piece i doubt it'll do you any good. If you are talking about medicinal grade MDMA its another thing entirely.

"Dr. Julie Holland, a psychiatrist at New York University, says MDMA holds promise as an aid to psychotherapy for some patients, if taken under the guidance of a trained therapist under tightly controlled conditions. The federal government has approved early human trials."
http://www.mdma.net/ecstasy/ecstasy-guide.html

It has been used in Holland for the purpose, but afaii they gave it up because of the controversy it created with other countries (not because it didnt work its purpose)

quote:

I could easily see good experiences on E helping people get perspective on issues which may be causing their depression, which could help them become un-depressed in the future

You just summed me up there.

quote:

I could easily see good experiences on E helping people get perspective on issues which may be causing their depression, which could help them become un-depressed in the future.

This is exactly it. It gives you a chance to look at things from another perspective, and a chance to enjoy a couple hours without the constant crush of stress and negative thoughts. I know that I usually come out of a night on pills feeling much better about myself and the world around me, and the first time I tried MDMA completely changed my outlook on life (for the better).

Of course this often leads to people abusing the drug heavily, which leads to shitty comedowns and fucking up your serotonin system, which would only compound any pre-existing depression. But taken safely, I think MDMA is something that can really help give you a much more positive outlook on life.

I dont know but I popped about a week ago and had a horrible trip. ive also been feeling worse since. i suppose it depends on the individual?

quote:

Originally posted by Taranis and the first time I tried MDMA completely changed my outlook on life (for the better).

that's retarded.

I need to trip balls for like 8 days on some substance.

quote:

Originally posted by silene So, i just finished skimming the study, and it turns out that the decreased levels of depression was determined solely from self-administered questionnaires give to the test subjects; not very reliable.

How else do you diagnose depression other than through subjective patient responses? Is there a blood test for depression out now that I'm not aware of?

quote:

Originally posted by Taranis This is exactly it. It gives you a chance to look at things from another perspective, and a chance to enjoy a couple hours without the constant crush of stress and negative thoughts. I know that I usually come out of a night on pills feeling much better about myself and the world around me, and the first time I tried MDMA completely changed my outlook on life (for the better). Of course this often leads to people abusing the drug heavily, which leads to shitty comedowns and fucking up your serotonin system, which would only compound any pre-existing depression. But taken safely, I think MDMA is something that can really help give you a much more positive outlook on life.

Before my first e trip, I was already a pretty social person with very few inhibitions and genuine love for others. The e just enhanced it by removing any self-doubts that remained, and that feeling carried over into the rest of my life ever since .

quote:

that's retarded.

What a constructive comment ; same as your previous one in this thread. Not everyone does mind-altering drugs just so they could have an excuse to be a retarded sweaty idiot. If approached with the right mindset, the possibilities for introspection are enormous.

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