Save your session under a different name (so you are sure you still have a good copy to revert to).
Bounce the tracks you are pretty certain that they are final to audio (either make it one stereo file for several tracks, or bounce each track you want to free apart, if you applied stereo effects, bounce to stereo). That way you'll get an audio file "with the effects integrated". Pure audiofiles don't strain the cpu that much (they put more strain on the harddisks, but a decent harddisk can take enough audio tracks).
The problem with this method is that if you see you need to change something to a track you already bounced (one of the effects is too pronounced for example), you need to revert to the "unbounced" version of your session. That's why I told you to save that session (another way of achieving a similar result is to keep the tracks you bounced, but disable everything on them (effects and soft instruments), that way if you wanna change something, you reactivate them and make the tweaks).
It's a bit of work, so some programmers thought of a feature called freeze, that can make temporary bounces to free up cpu. If you need to change something, you can unfreeze those tracks again. Problem is, Freeze is only a feature since Nuendo 2.1/Cubase SX 2, and it's not nearly as versatile as the Logic or Samplitude freeze feature.
If this all seems too much work for ya, there is a third party freeze plugin that's called FX Freeze that can do that freezing job pretty well.
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