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you need to start by cleaning up the samples individually one-by-one
If you have a kick drum that has unecessary high frequency sounds cut it out (but leave in the click from the kick)...
similarly, a high-hat does not benefit from any mid and low frequency sounds so cut those out
basses and kicks should both be low frequency but however i like to raise the 100 hz part of the kick a bit higher than normal and for the bass i like to raise it up higher either at 50 hz or 200 hz... this will make your lower end section more cleaner and distinguishible
finally, adjust the rest of the synths, fx, percussion so that they interfere with each other as little as possible by using EQing and panning
After you put everything together, and it sounds pretty good, you'll want to apply a bit of final EQ to the whole mix to adjust the bass, mid, treble... whatever needs a boost or whatever needs to be cut back a bit...
also compressing every component a bit will help... here's a helpful guide to get u started
http://www.computermusic.co.uk/tutorial/dynamics/3.asp
also, if you have a program like cool edit pro or soundforge, i think there is a remove noise option that will help a bit sometimes... but not all the times... sometimes it ends up worse than before... anyways, use this on the individual samples that you are having trouble with and that may help...
other than that, i don't really know if i can help
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