Alkylating agents - bi-functional DNA reactive drugs e.g. nitrogen mustards cyclophosphamide and melphalan, and platinum compounds cisplatin and carboplatin - bind DNA causing cross-strand links
Antimetabolites - decrease precursors for DNA synthesis, e.g. 5-Flourouracil, methotrexate
Topoisomerase inhibitors - inhibit DNA replication by binding the "cleavable complex" of topoisomerase preventing the DNA's dissociation form the protein e.g. etoposide, doxorubicin
Incorporation into DNA strand as analogues of normal nucleotides leading to mutation e.g. 5-FU, 6-mercaptopurine
Mitotic spindle poisons - inhibit formation microtubules etc. preventing mitosis e.g. vincristine, taxol

Thus all causing probs for DNA and cell replication, promoting apoptosis and destruction of said cancer cells
Unless you have p53 mutations, Bcl-2 overexpression, then your fucked


cheers for the revision opportunity

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All the weekend rockstars in the toilets
Practicing their lines

This post is better than your post

i have resorted to doing my revision the night before and morning of. never ever did i do this before, but i just reckon that out of everything i have learned the past years is exam technique, got it off to a 'T' but the real reason is that i have lost all motivation and dun give a fuck

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Art in the Park Courtesy of PISE & the Ravin' Beauties

good luck guys.i finished on monday and its worth putting in that little bit of effort over the next days and weeks and then u can properly enjoy ur summer

i never revised for longer than 15mins before coneeeding defeat, saying fuck it, and going in un-prepared.

i hate essay based exams and i think its a crock of shit you have to do them when ur doing a science degree

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Fave Tune at the Moment: Mesmerizer - Taking Control

>>> Download my mix here <<< (Electro, Techno & Psy-Trance)

i did good

All the things that i'm strong at, and i had prepared, came up

time for some hardcore substance abuse this weekend!!!!1!!

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The Midnight Collective MySpace

quote:

Originally posted by Ste i hate essay based exams and i think its a crock of shit you have to do them when ur doing a science degree

yeah MCQs all the way

tho a good essay question discriminates between those who simply have a good memory and those with the ability to apply their knowledge

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All the weekend rockstars in the toilets
Practicing their lines

This post is better than your post

quote:

Originally posted by swisstoni i have resorted to doing my revision the night before and morning of. never ever did i do this before, but i just reckon that out of everything i have learned the past years is exam technique, got it off to a 'T' but the real reason is that i have lost all motivation and dun give a fuck

I hear that.

I think I might take a year out next year. I think that right now, I lack the motivation to do my final year, so I think I'm gonna take a year out to practice what I've learnt and maybe get a job and save up a bit of dollar.

I just cant be arsed right now though.

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Revision sucks, doesn't it.

I've got history tomorrow, then that's no more exams for me this year and a week off school.

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Just when you thought this was over, it had only just begun...

i didn't revise ever

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MUGGETS

quote:

Originally posted by tu_face i didn't revise ever

congratulations