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Try to first test out your audio connections by connecting gear that you know works for sure. If that's not the case, try this:
press both "Edit" and "Sync" buttons together next to "FM" knob - this should audition the currently selected patch for you. Also, check your HD interface patching. Oftentimes you need to route your analog in to main out. I had quite a bit of hard time getting that to work on Presonus Firestation.
You can also try recording something in your DAW - if you see audio signal show up in an audio track, then you probably have a setting that wasn't checked on your hd interface. Some recording interfaces don't offer ZLM (zero latency monitoring) and rely on DAW applications (such as Cubase) to route the audio signal.
If you are using Cubase, make sure you have enabled monitoring on the track.
When all else fails, RTFM. (Read That Friendly Manual) 
cheers!
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Proud member of the "Filthy Zionist" coalition
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