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Try to move the cables away from anything which might create interferece. Such as your monitor, other speakers, your computer, high powered electro-magnets, etc. 
Also I think it is possible for the fans inside your computer to create distortion on the actual sound card (cpu fan does that to my video card ) so if youve got some kind of big vacuum sucker fan in there, probably a good idea to swap it for something a bit more humble.
The other thing which can cause noise is when youve got the volume too high on the speakers and too low on your sound card / mixer (this may not be the case with a digital connection i dunno). Go into the delta control panel and make sure youre running all the outputs through the delta mixer, then make sure all the volumes are correct for your speakers (nominal input?)
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