Here is my filing system, I use 3 drives.
Drive A: 120GB - Only applications and my design and client files.
Drive B: 120GB - Music, Games, Downloads, test files, etc. I have a meticulous filing system where things get rotated and sent to the burn unit as I have multiple ftps going in and out. I sometimes go through 20+GB of data a week on this drive so I update it frequently.
Drive C: external 160GB - This drive is only used for backups at the moment. I have software that backs up crucial files. It is an external firewire/usb combo incase I need to bring to another computer for rescue or to share client files.
Really if you have a good file system you don't have to worry about a big mess. I have 90+GB free on drive A, I fluctuate between 20-90GB free on drive B and drive D has 90% free.
___________________
|