You mean line-out from the laptop, right? So you can preview monitor in 'phones on one channel plus output to your amplifier on the other stereo channel.
Assuming that, for a laptop that has Cardbus slot, there is the Echo Indigo DJ, I have had one about 5 years and I never remove it because it's so small & convenient. Sound is considered excellent by a lot of DJs (but a few people say it's not the best).
http://echoaudio.com/Products/CardB...igoDJ/index.php
For a laptop that has ExpressBus, Echo now has a very similar card for that type of slot, the Indigo DJx.
http://echoaudio.com/Products/Expre...goDJx/index.php
There are lots of USB & Firewire sound devices that others can tell you about or check the official forums for the software you will use.
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