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A dog can be a powerful and dangerous adversary. However, a human being should be in no serious danger as long as he or she does not panic. In a worst case scenario you can feed one arm to the dog by allowing it to bite down on the side of one arm (not the front and back, then it could puncture a major artery). Once the dog has a grip, it will usually not let go. In this position, you can use your other arm to go for the eye gouge which is almost certain victory as it will have no way to defend itself without releasing your arm (and it won't until it's too late).
If you don't want to be significantly injured, you must avoid being taken down by the dog if at all possible. This will be difficult if the dog is large for small or out of shape people, particularly women. Even a relatively small dog can take you down fairly reliably however if you let it get a grip on a leg. Larger dogs, especially aggressive breeds are likely to jump for your throat: if you react quickly and raise a knee this will be no threat - and if you can strike it in the larynx with your knee it will usually run away.
IMO the best strategy is to keep your moving like a boxer but instead of using your fists you use swift kicks to the head or the side of the dog's leg (if it is tall enough). Dogs are usually muscular in the neck, head, and torso, but their legs are injured easily. Try to take advantage of their weakness. A couple of strong kicks to the head will deter most dogs: just make sure to pull your foot back quickly so it cannot bite your ankle.
I've been attacked by a dog on two occasions, in both the dog jumped their owners' fences to attack me while I was jogging at night. By remaining calm and using my ability to attack from a small distance I was able to force both into retreat without sustaining even minor injuries. I do not believe a lone dog could ever pose a serious threat to me unless it caught me by surprise.
Lastly, a pen would only be useful if you were taken down. Again, you could give it one arm and stabbing the pen into an eye, nose, ear, or throat. Any of these would be painful enough to the dog that it would probably run away.
The best way to be safe is to be prepared. After reading this post you should have all the tools you need to survive a dog attack.
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