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135 tcp loc-srv Basic scan Remote Procedure Call (RPC) port 135 is used in client/server applications (might be on a single machine) such as Exchange clients, the recently exploited messenger service, as well as other Windows NT/2K/XP software. If you have remote users who VPN into your network, you might need to open this port on the firewall to allow access to the Exchange server.
There is a RPC (a RPC's Endpoint Mapper component) vulnerability in Windows NT where a malformed request to port 135 could cause denial of service (DoS). RPC contains a flaw that causes it to fail upon receipt of a request that contains a particular type of malformed data. To restore normal functionality victim has to reboot the system. Alternatively, you can upgrade/patch your OS (there is a patch downloadable from Microsoft), or you can close port 135.
MS Security Bulletin MS03-026 outlines another critical Buffer Overrun RPC vulnerability that can be exploited via ports 135, 139, 445, 593 (or any other specifically configured RPC port). You should filter the above mentioned ports at the firewall level and not allow RPC over an unsecure network, such as the Internet.
W32.Blaster.Worm is a widely spread worm that exploits the DCOM RPC vulnerability described above (MS Security Bulletin MS03-026). The worm allows remote access to an infected computer via ports 4444/tcp and 69/UDP, and spreads through port 135/tcp. To avoid being infected consider closing those ports.
Port is also used by Messenger Service (not MSN Messenger) and exploited in popup net send messenger spam: MSKB 330904. To stop the popups you'd need to filter port 135 at the firewall level or stop the messenger service. The service uses all the following ports: 135/tcp, 135/udp, 137/udp 138/udp, 139/tcp, 445/tcp.
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