I have an m box 2 running though a small mackie mixer........ Does this colour the overall sound coming through the monitors? Should I just go directly from my audio device to the monitors?

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it does but whether the change is relevant , probably not given your interface.

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I'm pretty sure your monitors will effect the colour the most.

cheers for reply..... think ive been having a bad mixing period! paranoid and blaming my tools! think my ears need washing out!

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http://www.facebook.com/tripleonemusic
www.soundcloud.com/tripleone
Releases
Tripleone - Nightlight
Tripleone - Shimmer of the Tide
Tripleone - Rusher E.P
Tripleone - Out of the Shadows
Tripleone - 12 Angels