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Slylee
love lockdown

Registered: May 2001
Location: Hollywood, FL
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i think that taking "e" is a very eye opening experience to yourself as a person. it definitely helped shape my personality today (which fucking rocks by the way ). it enlightens you to yourself and gives you some confidence and helps you meet people and just walk up to anyone and start chatting them up.
i did a lot of it in my late teen years and earlier 20's (like 20 and 21), but like someone said somewhere in the cor about "e"...too much of something can be bad. it's true. basically, moderation is key.
but if you have an addictive personality and/or you're depressed or have beend depressed in the past, i don't recommend taking it, or any drugs for that matter. you're gonna love it too much and depend on it for partying and being social, and the adverse effect will kick in once it's worn off...major mood swings and depression. unless of course u want to go through this...
| quote: | Originally posted by Lephaid
Well, the problem mostly arises from the oxidative stress MDMA puts on your brain (which is probably mostly caused by dopamine hopping on to serotonin re-uptake transporters and entering serotonergic terminals, then breaking down inside the neuron). The brain starts synthesizing up serotonin like it's going out of fashion, during which free radicals (oxidative molecules like hydroxyls) caused by MAOB metabolism attack the enzymes that the body uses to create more serotonin, as well as the axon terminal at the end of the neuron. The axon tends to be where the more permanent damage is located in the case of neurotoxicity. So by the time you come down on your roll, your brain has not only lost the ability to manufacture serotonin through enzymatic inactivation, but also for the serotonin to work effective because the receptors on the axon for serotonin to bind to are damaged. This is all do to free radicals.
There are ways to fight free radicals to probably reduce damage. My recommendation for a regimen is as follows:
-1 hours
Vitamin C - 1000 mg
Alpha Lipoic Acid - 500 mg
Green Tea Extract - 1 capsule
Co-Enzyme Q10 - 100mg
+1.5 hours
5HTP - 250mg (The reason the 5HTP is taken now and not beforehand is because levels of 5HTP don't actually start dropping until you're well into your roll. The reduction in 5HTP (and subsequently serotonin) is do to the inactivation of the enzyme that converts tryptophan to 5HTP naturally in your brain by free radicals, which in all hope the preload should be taking care of anyway)
+5 hours
Vitamin C - 1000 mg
Alpha Lipoic Acid - 500 mg
Green Tea Extract - 1 capsule
Co-Enzyme Q10 - 100mg
5HTP - 500mg
+12 hours
Vitamin C - 1000 mg
Alpha Lipoic Acid - 500 mg
Green Tea Extract - 1 capsule
Co-Enzyme Q10 - 100mg
5HTP - 250mg
+20 hours
Vitamin C - 1000 mg
Alpha Lipoic Acid - 500 mg
Green Tea Extract - 1 capsule
Co-Enzyme Q10 - 100mg
5HTP - 250mg
Then the same antioxidant mix daily for the next few days. This should theoretically heavily cut down on the (likely permanent if not prevented!) neurotoxicity induced by MDMA.
edit: scratch the lutein, i forgot that was progesterone which might cause mood swings and which probably is mucked up by first pass metabolism anyway. |
lol
yea so anyway, in my opinion, "e" just gets old after a while, but i'm glad i did it. but i sorta think maybe everyone should do it once. sorta kinda...just depends. there are exceptions. but i totally respect ppl who haven't done it and dont feel the need for it in their life and are generally happy people without it.
___________________

My soliloquy may be hard for some to swallow, but so is cod liver oil.
| quote: | Originally posted by notelfreak
man i can't believe i tried to come off as responsible in that other thread, i am so full of shit just don't tell anyone |
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Jul-31-2006 17:38
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colonelcrisp
Isn't Batshit Crazy

Registered: Apr 2003
Location: Ottawa
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I know a few people who cant do E anymore as they get really paranoid on it. but as for me, it has provided me with some of the more memorable moments in my life. i have had some amazing experiences on it, and i feel that i am now alot closer with some of my good friends because of it. all in all its a great experience. However i dont do it very frequently anymore, as when i do get into it, i tend to go big or go home, and as such, it takes alot out of me and it takes along time to recupperate.... but as long as i get to roll a couple times a year im happy as a pig in shit.
___________________
| quote: | Originally posted by pkcRAISTLIN
I have 3 hobbies: gaming, DJing & correcting maladjusted fools on the internet. |
| quote: | Originally posted by pkcRAISTLIN
Yeah, I’d like to know what horrible, scarring incident in your childhood turned you into such an ignorant, intellectual-hating philistine? |
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Jul-31-2006 18:47
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