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probably to late for Phil now, but this is what happens with the juices.
Orange Juice i.e Vitamin C is an antioxidant. When you take MDMA, and it gets metabolised in the brain, it produces free radical molecules (google some chemistry) They are highly reactive molecules that will react with anything very quickly. Antioxidants react with these molecules and prevent them from doing harm. Thus, by taking lots of vitamin c, you minimise brain damage. Free radicals are also responsible for aging, which is why some cainers look a lot older than they are...
Grapefruit Juice contains a molecule that acts as a carrier for 5htp. If you want to roll long and hard you should take a few 5htp's with grapefruit juice a few hours before you drop.
The carrier molecule does two things. It bings to 5htp and prevents its first pass metabolism by the liver. So you will have more 5htp floating around inside you. Furthermore, the carrier molecule helps the 5htp get into the brain easier, as through complex biochemistry it sort of changes the conformation of the 5htp so it can cross the blood brain barrier more effectively. Now because you now have more 5htp in your body, and now even more in your brain cos of the grapefruit juice, then seratonin production will be at maximal rate. Do this after you've rolled and you will greatly reduce any sort of comedown too.
(TA's resident Pharmacologist)
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