the best thing for after E sketch is a lil bit of K (i like a 1/10 of vial solution in water)

somebody wrote it on this board i tried it 3 times so far and worked like a charm (except the lil k trip) every single one of them

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Mr Kaizen on Soundcloud

quote:

Originally posted by LightsOut you need to take it on a regular basis leading up to an event in order to help restore seratonin.....from what ive been told

Bingo. Take 5-htp at least 3-4 days before you know you're going to pop, and a few days afterwards as well. Vitamin C is good, mint leaves/tea helps, dark chocolate, fruits veggies, gatorade to help restore all your lost electrolytes...

Taking 5-htp an hour before you go clubbing aint gonna do squat. Also invest in some multivitamins as well, they are great. And you can do them daily as well to keep you healthy

5HTP makes up for the lost 5HTP in your brain after MDMA permanently destroys tryptophan hydroxylase. The thing is, tryptophan hydroxylase damage is there to stay, so it really just serves to mask problems that will become more apparent in the long term... It's also suspected to cause heart problems because a lot of 5HTP taken orally is converted to serotonin before it gets into the brain, and thus interferes with cardiac function.

If you really wanna prevent the damage MDMA does to your brain, you probably just need to take a lot of antioxidants and not overdo it with your dosing (and don't take pills with meth in them!).

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Alcoholic Alliance
The Ecstasy (MDMA) Bible Thread 2.0

quote:

Originally posted by Masonious you win again dude - and nice move shoving the whole i figured out how to order pizza thing in my face. i tried that 4 and a half months ago and woke up with a Taiwanese transvestite but to Ygrene it's just, "anoother day in the life, noooo biggieee".

quote:

Originally posted by Fast Turtle 5HTP makes up for the lost 5HTP in your brain after MDMA permanently destroys tryptophan hydroxylase. The thing is, tryptophan hydroxylase damage is there to stay, so it really just serves to mask problems that will become more apparent in the long term... It's also suspected to cause heart problems because a lot of 5HTP taken orally is converted to serotonin before it gets into the brain, and thus interferes with cardiac function. If you really wanna prevent the damage MDMA does to your brain, you probably just need to take a lot of antioxidants and not overdo it with your dosing (and don't take pills with meth in them!).

This has not been scientifically proven. Research has yet to definitively determine whether changes to the brain caused by MDMA use are permanent/irreversible.

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Originally posted by PurpleHaze Bingo. Take 5-htp at least 3-4 days before you know you're going to pop, and a few days afterwards as well. Vitamin C is good, mint leaves/tea helps, dark chocolate, fruits veggies, gatorade to help restore all your lost electrolytes... Taking 5-htp an hour before you go clubbing aint gonna do squat. Also invest in some multivitamins as well, they are great. And you can do them daily as well to keep you healthy

It is indeed possible that I simply have not come across this opinion, but as of yet I have never read or heard someone suggest that taking 5-HTP prior to the event is necessary in order for maximum restorative benefit. Every time I have read the suggestion that 5-HTP should be used before an event it has always been directed at the question 'can using 5-HTP before an event increase one's high?' (which it will not). Do you have any links with respect to what you're saying bud? I'd be interesting in reading into this if there is any merit to it.

quote:

Originally posted by Fast Turtle 5HTP makes up for the lost 5HTP in your brain after MDMA permanently destroys tryptophan hydroxylase. The thing is, tryptophan hydroxylase damage is there to stay, so it really just serves to mask problems that will become more apparent in the long term... It's also suspected to cause heart problems because a lot of 5HTP taken orally is converted to serotonin before it gets into the brain, and thus interferes with cardiac function. If you really wanna prevent the damage MDMA does to your brain, you probably just need to take a lot of antioxidants and not overdo it with your dosing (and don't take pills with meth in them!).

Good point. If you wanna minimize neurotoxicity to your brain by MDMA you want to take antioxidants (tea, chocolate, beans, spinach...) and if you wanna go all the way you can take Prozac with it at the same time or a few hours after you pop too. Prozac is a serotonin reuptake inhibitor which blocks the free radicals from damaging your axons and synapses (getting into brain talk here but pretty much serotonin gets dumped into a little space between your neuronal pathways called synapses).

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Originally posted by cenik This has not been scientifically proven. Research has yet to definitively determine whether changes to the brain caused by MDMA use are permanent/irreversible.

Okay, sorry, it's only been proven in countless studies with rodents and primates, and human users show permanent cognitive deficits in every single study I've seen.

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Alcoholic Alliance
The Ecstasy (MDMA) Bible Thread 2.0

quote:

Originally posted by Masonious you win again dude - and nice move shoving the whole i figured out how to order pizza thing in my face. i tried that 4 and a half months ago and woke up with a Taiwanese transvestite but to Ygrene it's just, "anoother day in the life, noooo biggieee".

quote:

Originally posted by PurpleHaze Good point. If you wanna minimize neurotoxicity to your brain by MDMA you want to take antioxidants (tea, chocolate, beans, spinach...) and if you wanna go all the way you can take Prozac with it at the same time or a few hours after you pop too. Prozac is a serotonin reuptake inhibitor which blocks the free radicals from damaging your axons and synapses (getting into brain talk here but pretty much serotonin gets dumped into a little space between your neuronal pathways called synapses).

Not completely, it doesn't block reductions in 5-HIAA which is the major metabolite of serotonin, indicating that it is still neurotoxic, at least to tryptophan hydroxylase (in rodents).

Aside from that, if you take MDMA and fluoxetine (or even 5HTP) you put yourself at risk for serotonin syndrome.

Selegiline is supposed to prevent most of the neurotoxicity as well, but I'm still not convinced that it's safe to take with MDMA at all.

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Alcoholic Alliance
The Ecstasy (MDMA) Bible Thread 2.0

quote:

Originally posted by Masonious you win again dude - and nice move shoving the whole i figured out how to order pizza thing in my face. i tried that 4 and a half months ago and woke up with a Taiwanese transvestite but to Ygrene it's just, "anoother day in the life, noooo biggieee".

taking 5 htp a few days before a party definately does the trick, id reccomend not to take more than 1 pill tho as the one time i did a few days of 5 htp beforehand i rolled face like i had taken 3-4 pills.

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Originally posted by Fast Turtle Okay, sorry, it's only been proven in countless studies with rodents and primates, and human users show permanent cognitive deficits in every single study I've seen.

damn right, they had this chick on a tv program a few months ago that had lost half of her brain matter after partying every weekend for 3 years.

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Originally posted by emonster4life damn right, they had this chick on a tv program a few months ago that had lost half of her brain matter after partying every weekend for 3 years.

come on, either your being really sarcastic or the tv program was BSing a lot...if you lost HALF of your BRAIN MATTER (as in mass) you wouldnt be living to be on that show, trust me lol

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Originally posted by emonster4life damn right, they had this chick on a tv program a few months ago that had lost half of her brain matter after partying every weekend for 3 years.

LOL... I can't believe how you are sucked into the media here in America. I have seen official gov't reports OUTSIDE of the USA that prove otherwise.

I saw a report of a guy that took e almost every weekend for 5 years (they est. that he took 10k pills in that time). His cat-scan showed nothing different then a normal brain.

I'm not here to preach the use of mdma, but seriously dont believe EVERYTHING the media tells you...