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From The Merck Index:
Title: Paroxetine.
CAS Registry number: [61869-08- CAS name(s): (3 S - trans )-3-[(1,3-Benzodioxol-5-yl oxy)methyl]-4-(4-fluorophenyl)piperidine
Additional name(s): (minus)- trans- 4-( p- fluorophenyl)-3-[[3,4-(methylenedioxy)phenoxy]methyl]piperidine Drug code(s): FG-7051; BRL-
Molecular formula: C19H20FNO3
Percent Composition: C 69.29%, H 6.12%, F 5.77%, N 4.25%, O
Literature references: Serotonin (5-HT) uptake inhibitor. Prepn: J. A. Christensen, R. F. Squires, Ger. pat. 2,404,113; eidem, U.S. pats. 3,912,743; 4,007,196 (1974, 1975, 1977 all to Ferrosan); of crystalline hydrochloride hemihydrate: R. D. B. Barnes et al., Eur. pat. Appl. 223,403; U.S. pat. 4,721,723 (1987, 1988 both to Beecham). Characterization of serotonin inhibition: J. Buus Lassen, Eur. J. Pharmacol. 47, 351 (1978). Binding to serotonin transporter complex: E. Habert et al., ibid. 118, 107 (1985); in comparison with imip ramine, q.v.: S. Z. Langer et al., J. Recept. Res. 7, 499 (1987). Pharmacokine tics: J. Lund et al., Acta Pharmacol. Toxicol. 44, 289 (1979); J. Lund et al., ibid. 51, 351 (1982). HPLC determn in plasma: M. A. Brett et al., J. Chromatog. 419, 438 (1987). Clinical pharmacology: S. M. Hassan et al., Brit. J. Clin. Pharmacol. 19, 705 (1985). Comparison with amitriptyline, q.v., in treatment of depression: A. L. Laursen et al., Acta Psychiat. Scand. 71, 249 (1985); R. Battegay et al., Neuro psychobiology 13, 31 (1985). Review of pharmacology and therapeutic use: K. L. De chant, S. P. Clissold, Drugs 41, 225-253 (1991).
Derivative: Hydrochloride
Molecular Formula: C 19 H 20 FNO 3 .HCl.halfH 2
CAS Registry: [110429-35-1]; [78246-49-
Trade name(s): Aropax (SKB) , Deroxat (SKB) , Paxil (SKB) , Seroxat (SKB) .
Properties: Crys tals, mp 129-131degrees . Soly in water: 5.4 mg/ml.
Melting Point: 129-131degrees
In short, all Paxil contains the same drug, Paroxetine, although in varying amounts.
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