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I was trying to stay out of this, but I couldn't help it. Many good points have been made, here are a few more:
1. Yes, alcohol has huge social costs. Not only the things Tatgirl mentioned (effects on MANY parts of your body, drunk driving, alcohol poisoning\choking on your own vomit), but also domestic violence and other types of violence in which alcohol often plays a role. BTW, an extremely addictive substance. Remember, there was a prohibition in the 20's in the U.S. for a reason, but the government eventually gave up cuz people do what they want to do.
2. It is silly to lump all "drugs" into one group. I'll keep the discussion on E here for simplicity's sake. If there have been serious injuries from E use, it seems to me that is because it was illegal. The illegality means people can't always find a "safe" source or don't know how to do it properly (eg. taking too much, or drinking too little or too much). Now imagine you could get your favourite brand at the drugstore or bar where you know exactly what you're getting and how much of it, had clear instructions on what to do if you run into trouble (just like people taking their alcohol-poisoned friends to the hospital with no fear of consequences), etc etc. In other words, the "War on Drugs" seems to be the cause for most of the drug-related problems. This is a long debate though and not one I want to get into here.
3. There are no long-term data on consequences of using E (again, thanks to the War on Drugs ther is little or no research), so take as much risk as you're willing to, the less the better. I agree with others that you should not NEED drugs to have a good time, if you do then you may want to sit back and reflect on that. Even if MDMA was harmless, the fact that you never really know what's in the pills makes it risky.
4. The tax argument is a good one, but if E and other relatively harmless (I am NOT saying it's harmless, just that it seems not to be outright dangerous like say, heroin) drugs were legalized and provided in a safe manner, the gov could tax their use just like they do alcohol and cigarettes. Yeah, this will never happen in our lifetime.
5. I now fully understand what led to Tatgirl becoming so twisted. Stay away from drugs kids!!! 
Last edited by Arcticboy on Feb-10-2003 at 04:20
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