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moncster
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It's not like 5htp has no bad effects on the brain.

Old Post Nov-25-2003 03:15 
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jdjd
Supreme tranceaddict



Registered: Aug 2002
Location: sf

just take g and you dont have to worry about all that
how long does it take for e to 'go bad'!?

Old Post Nov-25-2003 03:19  United States
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Mike_B
Supreme tranceaddict



Registered: Oct 2002
Location: Montreal

5 htp doesn't harm you, its the main componant your body uses to create serotonin. Its found all over the place, Turkey had a high concentration of it.

as for http://www.erowid.org/chemicals/mdm..._article3.shtml

lol i used to read erowid all the time great source of info there.

Old Post Nov-25-2003 03:22  Canada
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Transattic
tranceaddict



Registered: Nov 2003
Location: Los Angeles (Westchester) - 1337 LATA

quote:
Originally posted by DJ-Fuq
Its a bit more complicated than that.
MDMA binds at the serotonin, norepinephrine (noradrenaline), dopamine, and acetylcholine receptors, and at the serotonin and dopamine transporters (Rivas-Vazquez, Delgado, 2002). It moves through the serotonin pathway, to the cell bodies in the Raphe nucleus and sends long axons to the neocortex, and the limbic system, and also descends the spinal cord to affect the motor neurons (NIDA, 2003).
MDMA's primary mechanism of action is by releasing 5-HT (serotonin)and blocking its reuptake (Palfai, Jankiewicz, 2001). It also increases the net release of norepinephrine, and dopamine, and blocks the reuptake of dopamine (Rivas-Vazquez, Delgado, 2002). MDMA stimulates serotonin efflux from plasma membrane vesicles and secretory vesicles (Rudnick, Wall, 1992). In the plasma membrane vesicles, MDMA inhibits serotonin transport by direct interaction with the sodium dependent transporter. MDMA inhibits ATP-dependent serotonin accumulation and stimulates efflux of previously accumulated serotonin (Rudnick, Wall, 1992). Usually after serotonin is released into the synaptic gap and is used, serotonin transporters move serotonin back into the presynaptic neuron to be metabolized. MDMA prevents the transporters from taking serotonin back into the presynaptic neuron. It can also cause the transporters to work in reverse bringing serotonin into the synaptic gap (NIDA, 2003).
http://www.humboldt.edu/~morgan/mdma_s03.htm


Busting out the Biology and Chemistry!!!
Looks like someone did their research, if not already a scientist.


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Strongbad is... Stinko Man!

Los Angeles Tranceaddict Alliance
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Old Post Nov-25-2003 03:55  Germany
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jdjd
Supreme tranceaddict



Registered: Aug 2002
Location: sf

cut and paste

Old Post Nov-25-2003 03:57  United States
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DJ-Fuq
gone



Registered: Apr 2002
Location: nowhere

quote:
Originally posted by jdjd
cut and paste


Yeah i only added a couple of things in brackets for clarity

Old Post Nov-25-2003 04:02 
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Transattic
tranceaddict



Registered: Nov 2003
Location: Los Angeles (Westchester) - 1337 LATA

what do u mean, bud?


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Strongbad is... Stinko Man!

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Old Post Nov-25-2003 04:03  Germany
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moncster
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quote:
Originally posted by jdjd
cut and paste


http://www.humboldt.edu/~morgan/mdma_s03.htm

y halo thar!

Old Post Nov-25-2003 04:27 
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neoh
I prefer drum and bass!@#



Registered: Nov 2003
Location: /root

quote:
Originally posted by jdjd
just take g and you dont have to worry about all that
how long does it take for e to 'go bad'!?


E will last forevor, even in warm climates.

- neoh

Old Post Nov-25-2003 05:32  Canada
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A.J.
Back from the dead



Registered: Nov 2003
Location: Sydney

quote:
Originally posted by KilldaDJ
'course i been taking the pills, what do u think ive been doing with them? sticking them up my arse?' ROFL



Have you heard of shelving??? (as in sticking drugs up your ass)

Old Post Nov-25-2003 09:13  Australia
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UglyDave
i ran a marathon : )



Registered: Jan 2003
Location: Buncrana, Éire

quote:
Originally posted by DJ-Fuq
Its a bit more complicated than that.
MDMA binds at the serotonin, norepinephrine (noradrenaline), dopamine, and acetylcholine receptors, and at the serotonin and dopamine transporters (Rivas-Vazquez, Delgado, 2002). It moves through the serotonin pathway, to the cell bodies in the Raphe nucleus and sends long axons to the neocortex, and the limbic system, and also descends the spinal cord to affect the motor neurons (NIDA, 2003).
MDMA's primary mechanism of action is by releasing 5-HT (serotonin)and blocking its reuptake (Palfai, Jankiewicz, 2001). It also
...
...
...


respect to this guy! he knows everything!!

Old Post Nov-25-2003 09:52  Ireland
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PSi
Come to Daddy



Registered: Feb 2001
Location: Fort McMurray, AB

quote:
Originally posted by UglyDave
i've heard.. although i'm not sure about how true it is, but.. aparrently, if u stick a pill up ur ass it supposedly gives u a great buzz.

althoigh i'd seriously doubt this, and the actual stuff will have no effect on the part of the body it comes in contact with.. the pills will only affect u when the mdma gets into ur brain and pops all those little cells which hold ur seratonin and and awahey u go!!

UglyDave


yeah when you take a pill up your bum (for the record i havent tried this) it works just as well as say snorting it. The chemicals are easily absorbed by the large amount of blood running around your anal Spongebob.

Note of advice: dont chew pills, let your ass do the chewing for you.

later,
PSi

Old Post Nov-25-2003 11:36  Canada
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