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Mixing chemicals is fun!
| quote: | Originally posted by DJ Kenosis
Guys, a lot of people, including me, like you both, and it's frustrating to see this going on. This isn't solving anything.
Besides, there are more important things to argue about. Such as whether N body codes such as Mercury 6 can be used to accurately model the accretion of planetesimals, modeled as having zero mass, onto a protoplanet since the gravitational field within the Hill radius of the protoplanet is dominated by the protoplanet itself ...OR...whether N body codes are insufficient as they fail to take into account the gravitational stirring of planetesimals by themselves which lead to collisions, a fundamental change in the mass (and thus velocity) spectrum of the planetesimals and which may allow the accretion of shear-dominated, as opposed to dispersion dominated, plantesimals to ...well, dominate, driving down the formation timescale for said protoplanets. I mean, c'mon, that's on everyone's mind here at work at least :P |
Well when conducting nucleophilic acyl substitution reactions of carboxylic acids the direct nucleophilic substitution of the carboxylic acid is difficult because -OH is a poor leaving group. So to enhance reactivity I either have to use a strong acid catalyst to protonate the carboxyl and make it a better acceptor or convert the -OH into a better leaving group. Although under the right conditions I have found that acid chlorides, anhydrides, esters, and amides can be prepared from carboxylic acids. 
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