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I suppose you could, depending on the time signature, but for standard 4/4 music, it just won't sound right. I'd be the last person on here to advocate formulas for arrangement, but the 4*N-bar "rule" is a pretty solid one that you should follow unless you're writing really unconventional music. And when I say unconventional I mean outside the realm of trance/techno/house and really any western music at all.
That's not to say you can't have motifs, fills, or other interludes that are 1 bar or 3 bars or 7 bars - that's a good technique to grab the listener's attention. The melody as a staple of the track, though, really has to be either 2 bars or a multiple of 4.
Jazz is different, and there's a fair amount of classical music that breaks the rule, but again, if you're talking about EDM (i.e. dance-floor music) then you don't want to throw off people's sense of rhythm.
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