I've got Reason rewired to Ableton. Generaly have no problems.

I'm having a strange issue though... I'm using the Combinator and for some reason, whenever I hit play, the "Run Pattern Devices" button keeps turning back on after I turn it off?? Really frustrating... and it's making it really difficult to record because every time I stop the song, then hit play, it's back... and the first thing I have to do is quickly deactivate that button... anybody had this issue? Any ideas that can help?

I think it's supposed to do that. Deactivate the pattern device within instead.

Yup, dumb mistake... left the Matrix in and pattern button on. Thank you!