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I use Trilogy and sometimes Absynth for sub-basses.
Really though, depending on the track you're making, it's going to depend on the timbre, volume, mixing with the rest of the track, etc. You might be able to make an isolated bass sound as clean as you want it to but it won't matter unless it works well in the overall mix.
Unfortunately if there are any tricks to doing that, I don't know them.
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