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Depends what comp you got, and wot Operating system you have, windows XP pro has a very good ram management system, and doesnt keep memory after programs r used, and refreshes it 
As for cpu, yeah winamp visualisations will use a bit, nothign major though.
THe things that kill yr comp r all the stuff u have running in yr taskbar, and in the background, like spyware, etc 
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