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Tylenol and alcohol warning (pg. 2)
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| nchs09 |
i had a buddy who would drink tylenol pm after drinking casue they were free @ his school.
after he offered me one i was like
"ahh dude i dont think ur supposed to take alcohol with tylen"
he was like
"but they help me sleep so well dude...."
and i read the back of the bottle to find exactly what u found.. it wont kill you, just take the pills... its bad for your liver.
but having said that, what isnt bad for your liver:disbelief |
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| jdat |
| quote: | Originally posted by nchs09
i had a buddy who would drink tylenol pm after drinking casue they were free @ his school.
after he offered me one i was like
"ahh dude i dont think ur supposed to take alcohol with tylen"
he was like
"but they help me sleep so well dude...."
and i read the back of the bottle to find exactly what u found.. it wont kill you, just take the pills... its bad for your liver.
but having said that, what isnt bad for your liver:disbelief |
any form of acetaminophen can cause long term problems to your liver if used abusively
read the erowid :p |
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| nchs09 |
| quote: | Originally posted by jdat
any form of acetaminophen can cause long term problems to your liver if used abusively
read the erowid :p |
ya i know its bad for the liver...
all im saying is that.. it wont kill him since i know my buddy was doing it for like 3 months...
he still drinks hardcore now... and hes fine |
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| Slylee |
| i think it's just tylenol u can't mix...ibprofen should be alright |
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| XaNaX |
Its not like mixing tylenol and alcohol will make you drop dead that instant. Well I guess it could, if you took extreme amounts of acetaminophen like a heavy vicodin addict might and then drank a lot also you could cause liver failure due to an overdose of the combination of alcohol and acetaminophen.
But typically what happens is over the course of months or years of abuse the damage to your liver adds up and your liver ends up failing. The combination of the two increases the damage to your liver quite a bit over what either of them do individually, that is why they tell you not to take it if you typically consume more than three drinks in a day. |
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| spiflicated |
Found this on medicinenet.com:
How does an overdose of acetaminophen cause liver injury?
The answer is that liver damage from acetaminophen occurs when the glutathione pathway is overwhelmed by too much of acetaminophen's metabolite, NAPQI. Then, this toxic compound accumulates in the liver and causes the damage. Furthermore, alcohol and certain medications such as phenobarbital, phenytoin, or carbamezepine (anti-seizure medications) or isoniazid (anti-TB drug) can significantly increase the damage. They do this by making the cytochrome P-450 system in the liver more active. This increased P-450 activity, as you might expect, results in an increased formation of NAPQI from the acetaminophen. Additionally, chronic alcohol use, as well as the fasting state or poor nutrition, can each deplete the liver's glutathione. So, alcohol both increases the toxic compound and decreases the detoxifying material. Accordingly, the bottom line in an acetaminophen overdose is that when the amount of NAPQI is too much for the available glutathione to detoxify, liver damage occurs. |
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| guster |
Yah take Ibuprofen instead. Both acetaminophen and alcohol are metabolised in the liver, which can overwork it and cause damage..
Ibuprofen however is metabolised in the kidneys if I remember correctly, so that'd be safer. |
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| Omega_M |
| stop drinking too much. |
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| XaNaX |
| quote: | Originally posted by Omega_M
stop drinking too much. |
Why would you do that when you can just take ibuprofen instead? |
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| Omega_M |
| quote: | Originally posted by XaNaX
Why would you do that when you can just take ibuprofen instead? |
cause that's the source of the problem. |
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| XaNaX |
| quote: | Originally posted by Omega_M
cause that's the source of the problem. |
No, the acetaminophen is the source of the problem. Drinking with other pain killers like ibuprofen is just fine. |
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| Omega_M |
Atleast in 1998, the FDA had issued this warning.
| quote: | FDA ANNOUNCES NEW ALCOHOL WARNINGS FOR PAIN RELIEVERS AND FEVER REDUCERS
The Food and Drug Administration announced today that all over-the-counter (OTC) pain relievers and fever reducers must carry a warning label advising people who consume three or more alcoholic drinks every day to consult their doctors before using these drugs.
This announcement is based on a final rule, which is on display today in the Federal Register, requiring manufacturers to add this warning to the labeling within six months for OTC products and combination products intended for adult use that contain aspirin, other salicylates, acetaminophen, ibuprofen, naproxen sodium, or ketoprofen.
FDA is issuing this final rule after considering public comments and data on the effect of combining chronic alcohol ingestion and the use of various OTC analgesics. The action also follows the recommendations of the Nonprescription Drugs Advisory Committee and the Arthritis Drugs Advisory Committee which concluded that chronic alcohol users should be warned that they may be at an increased risk of liver damage or stomach bleeding from use of these drugs.
Today's comprehensive action provides for an alcohol warning on all OTC pain relievers and fever reducers intended for adult use and may help prevent serious side effects in people who consume three or more alcoholic drinks every day.
The specific warnings concerning "liver damage" and "stomach bleeding" are being required because the agency believes that consumers with a history of chronic alcohol use need to know the potential risk that use of OTC analgesic and antipyretic (fever reducing) drug products may pose to them.
"Consumers need to know that chronic use of alcohol while taking pain relievers or fever reducers can be hazardous to their health. FDA urges people with a history of alcohol use to seek a doctor's advice about their risk of side effects before taking these medications," said Dr. Michael A. Friedman, Acting FDA Commissioner.
FDA's final rule, includes the following specific warnings:
* Acetaminophen: "Alcohol Warning: If you consume 3 or more alcoholic drinks every day, ask your doctor whether you should take acetaminophen or other pain relievers/fever reducers. Acetaminophen may cause liver damage."
* Aspirin, carbaspirin calcium, choline salicylate, ibuprofen, ketoprofen, magnesium salicylate, naproxen sodium and sodium salicylate: "Alcohol Warning: If you consume 3 or more alcoholic drinks every day, ask your doctor whether you should take [ingredient] or other pain relievers/fever reducers. [Ingredient] may cause stomach bleeding."
* Combination of acetaminophen with other analgesic/antipyretic ingredients: "Alcohol Warning" "If you consume 3 or more alcoholic drinks every day, ask your doctor whether you should take [insert ingredients] or other pain relievers/fever reducers. [Insert ingredients] may cause liver damage and stomach bleeding.
According to the Substance Abuse and Mental Health Service Administration report, "Preliminary Results from the l997 National Household Survey on Drug Abuse," about 11 million Americans are heavy drinkers. These people, therefore, are at risk of the serious side effects that may be posed by the combination of heavy alcohol use and analgesics or antipyretics labeled for OTC adult use.
New OTC pain relievers and fever reducers approved for OTC adult use since 1993 have already been required to carry a warning for heavy alcohol users. However, labeling to indicate the specific risk associated with each ingredient has not been required. Products previously required to include an alcohol warning in their labeling include Aleve (naproxyn sodium), Orudis KT and Actron (ketoprofen), Advil Liquigels (solubilized ibuprofen), and Tylenol Extended Release (acetominophen). These products will also be subject to the new rule. |
Source
THere is also a paper, but I could not access it since I'm not in the University.
KIDNEY FAILURE FROM A COMBINATION OF IBUPROFEN AND ALCOHOL
Link
My point is, you never know what could happen if you mix booze with these drugs. Be safe. Don't drink too much. Or, if you suffer from hangover then just sleep it out or something. |
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